STING and IFN-κ down-regulation in HPV positive clinical specimens.
- Nuchsupha Sunthamala (533002)
- Francoise Thierry (5658214)
- Sebastien Teissier (5658217)
- Chamsai Pientong (533003)
- Bunkerd Kongyingyoes (533004)
- Thumwadee Tangsiriwatthana (533005)
- Ussanee Sangkomkamhang (533006)
- Tipaya Ekalaksananan (533007)
Publication date
March 2014
DOIAbstract
<p>(A) HPV E2s transcription level was significantly increased in HPV positive normal and LSIL when compared to HPV negative normal cases (<i>P</i><0.05). (B) STING transcription level was significantly decreased in LSIL with HPV positive and HPV E2 positive cases (<i>P</i><0.05). Normal cases with HPV positive also showed low STING transcription level when compared to normal HPV negative cases (<i>P</i><0.05). (C) IFN-κ transcription level was significantly down-regulated in normal HPV positive cases and HPV positive LSIL cases when compared to normal HPV negative cases (<i>P</i><0.05). (*<i>P</i>≤0.05, **<i>P</i>≤0.01, ***<i>P</i>≤0.001).</p
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