STING and IFN-κ transcripts were down-regulated by HPV E2s.
- Nuchsupha Sunthamala (533002)
- Francoise Thierry (5658214)
- Sebastien Teissier (5658217)
- Chamsai Pientong (533003)
- Bunkerd Kongyingyoes (533004)
- Thumwadee Tangsiriwatthana (533005)
- Ussanee Sangkomkamhang (533006)
- Tipaya Ekalaksananan (533007)
Publication date
March 2014
DOIAbstract
<p>(A) STING transcripts level analyzed by RT-PCR was significantly down-regulated by HPV16 E2, HPV18 E2 and the HPV18 E2 TAD in HPK and B) IFN-κ transcription level was significantly down-regulated by HPV16 E2, HPV18 E2 and HPV18 TAD in HPK. C) STING transcripts level was modulated by E2 in NUH49 as shown in (A). D) IFN-κ transcripts level was modulated by E2 in ITB3 and NUH49 as in (B). (A–D) HPV18 E2TAD significantly down-regulated STING and IFN-κ genes transcription when compared to HPV18 E2DBD. (*<i>P</i>≤0.05, **<i>P</i>≤0.01, ***<i>P</i>≤0.001).</p
Add to ORKG