Nar regulates ERK1/2-CREB signaling in NSCs proliferation.

<p>Western blot was used to detect the expression of p-ERK1/2 and p-CREB in NSCs after treatment with Nar for 3 d. We found that Nar could promote the expression of p-ERK1/2 (A) and p-CREB (B), which was inhibited partly by PD98059, an inhibitor of mitogen-activated protein kinase kinase 1 (MEK1). The western blot experiment was repeated three times. * P<0.05, compared with vehicle.