Kaplan-Meier curves for overall survival.

<p>TGF-β, HIF-1α, VEGF and pERK 1/2 overexpression were divided into an overexpression group and a weak-expression group. A log-rank test was used to calculate significance. A. Overall survival curves stratified by TGF-β expression (<i>P</i> = 0.139). B. Overall survival curves stratified by HIF-1α expression (<i>P</i> = 0.000). C. Overall survival curves stratified by VEGF expression (<i>P</i> = 0.217). D. Overall survival curves stratified by pERK 1/2 expression (<i>P</i> = 0.018).