Serotype-specific geometric mean OPA titers before and after the booster at 40 and 41 months of age with t-tests.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

Publication date

March 2014

DOI

10.1371/journal.pone.0091413.t005

Abstract

**P value from independent samples t-test using Satterthwaites method for unequal variances where appropriate.†Serotypes only present in PCV-13 vaccine.</p

Extracted data

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Serotype-specific geometric mean OPA titers before and after the booster at 40 and 41 months of age with t-tests.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

Open link

Publication date

March 2014

DOI

10.1371/journal.pone.0091413.t005

Abstract

**P value from independent samples t-test using Satterthwaites method for unequal variances where appropriate.†Serotypes only present in PCV-13 vaccine.</p

Extracted data

William S. Pomat (381258)
Anita H. J. van den Biggelaar (163091)
Suparat Phuanukoonnon (381259)
Jacinta Francis (381260)
Peter Jacoby (140921)
Peter M. Siba (136849)
Michael P. Alpers (214198)
John C. Reeder (137922)
Patrick G. Holt (136255)
Peter C. Richmond (112578)
Deborah Lehmann (381261)

February 2013

To demonstrate immunological memory, PPV was administered at 9 months of age and the mean (and 95...

Pneumococcal serotype-specific IgG geometric mean concentration before and after PHiD-CV or control vaccine.

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Pneumococcal serotype-specific IgG geometric mean concentration with 95% confidence interval amon...

IPD cases by age and vaccine serotype coverage.

Gili Regev-Yochay (311310)
Galia Rahav (311303)
Klaris Riesenberg (384538)
Yonit Wiener-Well (520951)
Jacob Strahilevitz (520952)
Michal Stein (520953)
Daniel Glikman (520954)
Gabriel Weber (520955)
Israel Potasman (520956)
Ron Dagan (57723)

February 2014

Dark grey – serotypes included in PCV7 (VT7), light grey – serotypes included in PCV13 (but not 7...

Serotype-specific geometric mean concentrations before and after the booster at 40 and 41 months of age with t-tests.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

**P value from independent samples t-test using Satterthwaites method for unequal variances where...

Proportion of participants with serotype-specific OPA titers ≥8.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

*Binomial exact confidence interval;**P Value from chi-square test of proportions at 40 mo...

Proportion of participants with serotype-specific IgG concentrations and OPA titers above thresholds.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

Proportion of participants with serotype-specific IgG concentrations and OPA titers above a thres...

Age-specific geometric mean serotype-specific antibody concentrations pre-and post-PCV7 at 0-1-2 or 1-2-3-months or no PCV7.

William S. Pomat (381258)
Anita H. J. van den Biggelaar (163091)
Suparat Phuanukoonnon (381259)
Jacinta Francis (381260)
Peter Jacoby (140921)
Peter M. Siba (136849)
Michael P. Alpers (214198)
John C. Reeder (137922)
Patrick G. Holt (136255)
Peter C. Richmond (112578)
Deborah Lehmann (381261)

February 2013

Geometric mean (GM) concentrations and 95% confidence intervals of serotype-specific IgG antibodi...

Proportion of participants with serotype-specific IgG concentrations ≥0.35 µg/ml.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

*Binomial exact confidence interval;**P Value from chi-square test of proportions at 40 mo...

Distribution of serotypes of cases included in the study according to the receipt of any dose of PCV13 vaccinea.

Ángela Domínguez (4353922)
Pilar Ciruela (314318)
Sergi Hernández (3547127)
Juan José García-García (4353919)
Núria Soldevila (2175832)
Conchita Izquierdo (3547133)
Fernando Moraga-Llop (4353892)
Alvaro Díaz (4353910)
Mariona F. de Sevilla (698457)
Sebastià González-Peris (4353913)
Magda Campins (4353901)
Sonia Uriona (4353904)
Johanna Martínez-Osorio (4353907)
Anna Solé-Ribalta (4353895)
Gemma Codina (4353889)
Cristina Esteva (2556901)
Ana María Planes (4353898)
Carmen Muñoz-Almagro (314323)
Luis Salleras (4353916)

August 2017

ONV = Other non-PCV13 serotypes aAny child who received only PCV7 or PCV10 was exclude...

Pneumococcal serotype-specific opsonophagocytic activity geometric mean titer before and after PHiD-CV or control vaccine.

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Pneumococcal serotype-specific opsonophagocytic activity geometric mean titer and 95% confidence ...

Proportion of participants with serotype-specific IgG ≥0.35 mcg/mL (A) and OPA≥8 (B).

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Proportion of children aged 12–59 months with serotype-specific IgG ≥0.35 mcg/mL (A) and OPA≥8 (B...

Comparison (t-test) between 23vPPV and PCV7 for OPA in GMT (titre−1).

C. Raina MacIntyre (126428)
Iman Ridda (436890)
Zhanhai Gao (126426)
Aye M. Moa (554887)
Peter B. McIntyre (93008)
John S. Sullivan (554888)
Thomas R. Jones (554889)
Andrew Hayen (137552)
Richard I. Lindley (126404)

April 2014

aRatio of PCV7 to 23vPPV.bThe number of samples tested for each stereotype varied dependin...

Concentrations of serotype-specific IgG from sera collected post-booster from PCV7 and PCV13 recipients.

Lindsay R. Grant (462217)
Sarah E. O’Brien (462218)
Polly Burbidge (462219)
Mitch Haston (286963)
Marta Zancolli (462220)
Lucy Cowell (462221)
Marina Johnson (462222)
Robert C. Weatherholtz (462223)
Raymond Reid (462224)
Mathuram Santosham (174287)
Katherine L. O’Brien (462225)
David Goldblatt (160742)

September 2013

Concentrations of serotype-specific IgG from sera collected post-booster from PCV7 and PCV13 reci...

Antibody geometric mean concentrations (GMC) after booster doses (pre and post) of acellular pertussis vaccine compained with tetanus and diphtheria toxoidsin 355 adolescent subjects with MBL wild type (A/A), heterozygotes variant type A/O (A/B, A/C, A/D) and homozygote variant type O/O (B/B, B/D, D/D, C/D, C/C).

Kirsi Gröndahl-Yli-Hannuksela (341975)
Juho Vuononvirta (341973)
Ville Peltola (341978)
Jussi Mertsola (219426)
Qiushui He (94554)

February 2014

Abbreviations: GMC, geometric mean concentration; CI, confidence interval; *Kruskal-Wallis test f...

Age-specific seroprevalence of IgG-Ptx concentrations in children 0–9 years of age in 1995-96 (upper figure) and in 2006-07 (lower figure).

Sabine C. de Greeff (339580)
Hester E. de Melker (120072)
Pieter G. M. van Gageldonk (359166)
Joop F. P. Schellekens (239594)
Fiona R. M. van der Klis (120069)
Liesbeth Mollema (359167)
Frits R. Mooi (133175)
Guy A. M. Berbers (120064)

February 2013

Note: on the x-axis the age-group, number tested and in brackets the percentage targeted by the a...

Geometric mean fold rise in antibody for PCV7-serotypes following PPV at age 9 months.

William S. Pomat (381258)
Anita H. J. van den Biggelaar (163091)
Suparat Phuanukoonnon (381259)
Jacinta Francis (381260)
Peter Jacoby (140921)
Peter M. Siba (136849)
Michael P. Alpers (214198)
John C. Reeder (137922)
Patrick G. Holt (136255)
Peter C. Richmond (112578)
Deborah Lehmann (381261)

February 2013

To demonstrate immunological memory, PPV was administered at 9 months of age and the mean (and 95...

Pneumococcal serotype-specific IgG geometric mean concentration before and after PHiD-CV or control vaccine.

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Pneumococcal serotype-specific IgG geometric mean concentration with 95% confidence interval amon...

IPD cases by age and vaccine serotype coverage.

Gili Regev-Yochay (311310)
Galia Rahav (311303)
Klaris Riesenberg (384538)
Yonit Wiener-Well (520951)
Jacob Strahilevitz (520952)
Michal Stein (520953)
Daniel Glikman (520954)
Gabriel Weber (520955)
Israel Potasman (520956)
Ron Dagan (57723)

February 2014

Dark grey – serotypes included in PCV7 (VT7), light grey – serotypes included in PCV13 (but not 7...

Serotype-specific geometric mean concentrations before and after the booster at 40 and 41 months of age with t-tests.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

**P value from independent samples t-test using Satterthwaites method for unequal variances where...

Proportion of participants with serotype-specific IgG concentrations and OPA titers above thresholds.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

Proportion of participants with serotype-specific IgG concentrations and OPA titers above a thres...

Age-specific geometric mean serotype-specific antibody concentrations pre-and post-PCV7 at 0-1-2 or 1-2-3-months or no PCV7.

William S. Pomat (381258)
Anita H. J. van den Biggelaar (163091)
Suparat Phuanukoonnon (381259)
Jacinta Francis (381260)
Peter Jacoby (140921)
Peter M. Siba (136849)
Michael P. Alpers (214198)
John C. Reeder (137922)
Patrick G. Holt (136255)
Peter C. Richmond (112578)
Deborah Lehmann (381261)

February 2013

Geometric mean (GM) concentrations and 95% confidence intervals of serotype-specific IgG antibodi...

Proportion of participants with serotype-specific IgG concentrations ≥0.35 µg/ml.

Johannes Trück (533548)
Matthew D. Snape (533549)
Florencia Tatangeli (533550)
Merryn Voysey (255058)
Ly-Mee Yu (44961)
Saul N. Faust (415924)
Paul T. Heath (533551)
Adam Finn (23223)
Andrew J. Pollard (44971)

March 2014

*Binomial exact confidence interval;**P Value from chi-square test of proportions at 40 mo...

Distribution of serotypes of cases included in the study according to the receipt of any dose of PCV13 vaccinea.

Ángela Domínguez (4353922)
Pilar Ciruela (314318)
Sergi Hernández (3547127)
Juan José García-García (4353919)
Núria Soldevila (2175832)
Conchita Izquierdo (3547133)
Fernando Moraga-Llop (4353892)
Alvaro Díaz (4353910)
Mariona F. de Sevilla (698457)
Sebastià González-Peris (4353913)
Magda Campins (4353901)
Sonia Uriona (4353904)
Johanna Martínez-Osorio (4353907)
Anna Solé-Ribalta (4353895)
Gemma Codina (4353889)
Cristina Esteva (2556901)
Ana María Planes (4353898)
Carmen Muñoz-Almagro (314323)
Luis Salleras (4353916)

August 2017

ONV = Other non-PCV13 serotypes aAny child who received only PCV7 or PCV10 was exclude...

Pneumococcal serotype-specific opsonophagocytic activity geometric mean titer before and after PHiD-CV or control vaccine.

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Pneumococcal serotype-specific opsonophagocytic activity geometric mean titer and 95% confidence ...

Proportion of participants with serotype-specific IgG ≥0.35 mcg/mL (A) and OPA≥8 (B).

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Proportion of children aged 12–59 months with serotype-specific IgG ≥0.35 mcg/mL (A) and OPA≥8 (B...

Comparison (t-test) between 23vPPV and PCV7 for OPA in GMT (titre−1).

C. Raina MacIntyre (126428)
Iman Ridda (436890)
Zhanhai Gao (126426)
Aye M. Moa (554887)
Peter B. McIntyre (93008)
John S. Sullivan (554888)
Thomas R. Jones (554889)
Andrew Hayen (137552)
Richard I. Lindley (126404)

April 2014

aRatio of PCV7 to 23vPPV.bThe number of samples tested for each stereotype varied dependin...

Concentrations of serotype-specific IgG from sera collected post-booster from PCV7 and PCV13 recipients.

Lindsay R. Grant (462217)
Sarah E. O’Brien (462218)
Polly Burbidge (462219)
Mitch Haston (286963)
Marta Zancolli (462220)
Lucy Cowell (462221)
Marina Johnson (462222)
Robert C. Weatherholtz (462223)
Raymond Reid (462224)
Mathuram Santosham (174287)
Katherine L. O’Brien (462225)
David Goldblatt (160742)

September 2013

Concentrations of serotype-specific IgG from sera collected post-booster from PCV7 and PCV13 reci...

Kirsi Gröndahl-Yli-Hannuksela (341975)
Juho Vuononvirta (341973)
Ville Peltola (341978)
Jussi Mertsola (219426)
Qiushui He (94554)

February 2014

Abbreviations: GMC, geometric mean concentration; CI, confidence interval; *Kruskal-Wallis test f...

Age-specific seroprevalence of IgG-Ptx concentrations in children 0–9 years of age in 1995-96 (upper figure) and in 2006-07 (lower figure).

Sabine C. de Greeff (339580)
Hester E. de Melker (120072)
Pieter G. M. van Gageldonk (359166)
Joop F. P. Schellekens (239594)
Fiona R. M. van der Klis (120069)
Liesbeth Mollema (359167)
Frits R. Mooi (133175)
Guy A. M. Berbers (120064)

February 2013

Note: on the x-axis the age-group, number tested and in brackets the percentage targeted by the a...

Geometric mean fold rise in antibody for PCV7-serotypes following PPV at age 9 months.

William S. Pomat (381258)
Anita H. J. van den Biggelaar (163091)
Suparat Phuanukoonnon (381259)
Jacinta Francis (381260)
Peter Jacoby (140921)
Peter M. Siba (136849)
Michael P. Alpers (214198)
John C. Reeder (137922)
Patrick G. Holt (136255)
Peter C. Richmond (112578)
Deborah Lehmann (381261)

February 2013

To demonstrate immunological memory, PPV was administered at 9 months of age and the mean (and 95...

Pneumococcal serotype-specific IgG geometric mean concentration before and after PHiD-CV or control vaccine.

Laura L. Hammitt (512148)
John Ojal (512149)
Mahfudh Bashraheil (196995)
Susan C. Morpeth (512150)
Angela Karani (182177)
Ahsan Habib (512151)
Dorota Borys (512152)
David Goldblatt (160742)
J. Anthony G Scott (69001)

January 2014

Pneumococcal serotype-specific IgG geometric mean concentration with 95% confidence interval amon...

IPD cases by age and vaccine serotype coverage.

Gili Regev-Yochay (311310)
Galia Rahav (311303)
Klaris Riesenberg (384538)
Yonit Wiener-Well (520951)
Jacob Strahilevitz (520952)
Michal Stein (520953)
Daniel Glikman (520954)
Gabriel Weber (520955)
Israel Potasman (520956)
Ron Dagan (57723)

February 2014

Dark grey – serotypes included in PCV7 (VT7), light grey – serotypes included in PCV13 (but not 7...

Serotype-specific geometric mean OPA titers before and after the booster at 40 and 41 months of age with t-tests.

Abstract

Extracted data

Serotype-specific geometric mean OPA titers before and after the booster at 40 and 41 months of age with t-tests.

Abstract

Extracted data

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