<p>A blinded independent validation cohort composed of 40 freshly frozen ccRCC, papRCC, chRCC, UT-UC and normal kidney samples was also used to validate the discriminatory ability of the qRT-PCR verified deregulated miRNAs. The results were highly repeatable between the two cohorts, recapitulating the specificity of these miRNAs in each tumour group.</p
<p>The experiments confirmed the expression of 10 novel and 4 known miRNAs in the left ventricle (LV...
<p>Due to the small chRCC sample number (n = 3), no statistical significance could be gained. AUC, a...
) of target miRNAs with those of a stably expressed endogenous (EC) miRNA(s) from the same sample. D...
<p>Four-hundred and thirty-four miRNAs were statistically significantly deregulated in all RCC subty...
<p>Expression of deregulated miRNAs was evaluated in the validation cohort. MicroRNA expression leve...
<p>Median log<sub>2</sub> fold change expression levels of the 14 most up-regulated and 11 most down...
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
<p>AUC, area under the curve; S.E., standard error; 95% C.I., 95% confidence interval.</p
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
<p>The expression of 4 miRNAs (miR-192, miR-194, miR-21, and miR-200a) was evaluated using qRT-PCR i...
Background: miRNAs play important roles in multiple biological processes, and deregulation has been ...
) of target miRNAs with those of a stably expressed endogenous (EC) miRNA(s) from the same sample. D...
Background: miRNAs play important roles in multiple biological processes, and deregulation has been ...
<p>Blue bars represent the results from microarray, while red bars indicate the results from qRT-PCR...
<p>The experiments confirmed the expression of 10 novel and 4 known miRNAs in the left ventricle (LV...
<p>Due to the small chRCC sample number (n = 3), no statistical significance could be gained. AUC, a...
) of target miRNAs with those of a stably expressed endogenous (EC) miRNA(s) from the same sample. D...
<p>Four-hundred and thirty-four miRNAs were statistically significantly deregulated in all RCC subty...
<p>Expression of deregulated miRNAs was evaluated in the validation cohort. MicroRNA expression leve...
<p>Median log<sub>2</sub> fold change expression levels of the 14 most up-regulated and 11 most down...
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
<p>AUC, area under the curve; S.E., standard error; 95% C.I., 95% confidence interval.</p
Introduction: A prerequisite to accurate interpretation of RQ-PCR data is robust data normalization....
<p>The expression of 4 miRNAs (miR-192, miR-194, miR-21, and miR-200a) was evaluated using qRT-PCR i...
Background: miRNAs play important roles in multiple biological processes, and deregulation has been ...
) of target miRNAs with those of a stably expressed endogenous (EC) miRNA(s) from the same sample. D...
Background: miRNAs play important roles in multiple biological processes, and deregulation has been ...
<p>Blue bars represent the results from microarray, while red bars indicate the results from qRT-PCR...
<p>The experiments confirmed the expression of 10 novel and 4 known miRNAs in the left ventricle (LV...
<p>Due to the small chRCC sample number (n = 3), no statistical significance could be gained. AUC, a...
) of target miRNAs with those of a stably expressed endogenous (EC) miRNA(s) from the same sample. D...