<i>Burkholderia</i>-mediated activation of caspase-1 in macrophages is strain- dependent.

<p>Cleavage of caspases-1, -9, -7, and PARP was detected by immunoblot in cell lysates of C57BL/6 wild-type BMM infected with <i>B. pseudomallei</i> strains E8, K96243 (K9), E212, 1026b, and <i>B. thailandensis</i> strain E264 at MOI of (<b>A</b>) 50∶1 and (<b>B</b>) 200∶1 at 1.5 hours post infection. One experiment of at least three performed is shown. non-infected (n.i.).