<p>(A) IFN-γ was quantified at time zero and one month after each dose of rLdccys1. (B) IL-10 was quantified at time zero and one month after the third dose of rLdccys1 (n = 10 animals per group) <sup>*</sup><i>P</i><0.001; <sup>#</sup><i>P</i><0.05.</p
<p>PBMCs (1 million/ml) were stimulated or not with LPS (100 ng/ml), CpG-A (3 µg/ml) or imiquimod (1...
<p>Freshly isolated splenocytes from (A) 8 week or (B) 8 month old female B6 or B6.NZBc1c13 (c1c13) ...
<p>PBMCs were obtained from dogs at the time of diagnosis (pre) and 3 weeks post vaccination (post) ...
<p>Data are depicted in a bivariate correlation graph between individual clinical signs and levels o...
<p>Dogs were infected with <i>Leishmania infantum-chagasi</i> plus five pairs of <i>Lutzomyia longip...
<p>Each line represents a different dog, with individual colors representing different treatment gro...
<p>IFN-γ levels were measured using ELISA techniques. Induction of IFN-γ was detectable in dogs trea...
<p>(a) Plasma IFN-γ and (b) Plasma TNF-α concentrations in infected (n = 17), control (n = 8), infec...
<p>Measurement of cytokines in peripheral blood indicated greater concentrations of pro-inflammatory...
<p>Freshly isolated splenocytes from 8 week or 8 month old female B6 or B6.NZBc1c13 (c1c13) mice wer...
A specific commercially available ELISA procedure was used to determine IL10 concentration (pg/mL) i...
A specific commercially available ELISA procedure was used to determine IFN-γ concentration (pg/mL) ...
<p>The plasma levels of IL-10 were determined in uninfected-untreated naive mice and the distinct un...
There is limited information available on cytokine profiles in dogs with different degrees of diseas...
<p>PBMC were collected, cryopreserved, recovered, and stimulated as described in Materials and Metho...
<p>PBMCs (1 million/ml) were stimulated or not with LPS (100 ng/ml), CpG-A (3 µg/ml) or imiquimod (1...
<p>Freshly isolated splenocytes from (A) 8 week or (B) 8 month old female B6 or B6.NZBc1c13 (c1c13) ...
<p>PBMCs were obtained from dogs at the time of diagnosis (pre) and 3 weeks post vaccination (post) ...
<p>Data are depicted in a bivariate correlation graph between individual clinical signs and levels o...
<p>Dogs were infected with <i>Leishmania infantum-chagasi</i> plus five pairs of <i>Lutzomyia longip...
<p>Each line represents a different dog, with individual colors representing different treatment gro...
<p>IFN-γ levels were measured using ELISA techniques. Induction of IFN-γ was detectable in dogs trea...
<p>(a) Plasma IFN-γ and (b) Plasma TNF-α concentrations in infected (n = 17), control (n = 8), infec...
<p>Measurement of cytokines in peripheral blood indicated greater concentrations of pro-inflammatory...
<p>Freshly isolated splenocytes from 8 week or 8 month old female B6 or B6.NZBc1c13 (c1c13) mice wer...
A specific commercially available ELISA procedure was used to determine IL10 concentration (pg/mL) i...
A specific commercially available ELISA procedure was used to determine IFN-γ concentration (pg/mL) ...
<p>The plasma levels of IL-10 were determined in uninfected-untreated naive mice and the distinct un...
There is limited information available on cytokine profiles in dogs with different degrees of diseas...
<p>PBMC were collected, cryopreserved, recovered, and stimulated as described in Materials and Metho...
<p>PBMCs (1 million/ml) were stimulated or not with LPS (100 ng/ml), CpG-A (3 µg/ml) or imiquimod (1...
<p>Freshly isolated splenocytes from (A) 8 week or (B) 8 month old female B6 or B6.NZBc1c13 (c1c13) ...
<p>PBMCs were obtained from dogs at the time of diagnosis (pre) and 3 weeks post vaccination (post) ...