Accumulation of GPs within MLN after oral gavage.

<p>MLNs were collected from mice 15(Panels A,B) or 24 hrs (Panel C) after there had been gavaged with GPs. Tissues were cryosectioned, immunostained, and viewed by confocal laser scanning microscopy. (<b>Panel A</b>) Cryosections of MLN from vehicle-treated (i.e., PBS) animals. Tissue sections were stained for CD45R/B220 (blue) to detect B cells and CD11c⁺ (red; arrowheads) to detect DCs. (<b>Panels B-C</b>) Cryosections of MLN demonstrating that GPs (green; arrows) were regularly associated with CD11c⁺ DCs (red; arrowheads) In panel B the scale bar corresponds to 100 μm, while Panel C it is 50 μm.