Quantification of HIV-1 from plasma and PBMC pre- and post-chemotherapy.

<p><b>A</b>) Plasma HIV-1 RNA decreased for 5 patients, increased for 3 patients, and was below the limit of detection at both time points for 1 patient. Median viral load pre-chemotherapy was 1 copy/mL versus 4 copies/mL post-chemotherapy. Open symbols indicate undetectable samples. <b>B</b>) Total HIV-1 DNA levels per 10⁶ CD4+ cells decreased in 4 patients and increased in 5 patients. Median HIV-1 DNA levels per 10⁶ CD4+ cells decreased from 355 to 228 copies per 10⁶ CD4+ cells from pre- to post-chemotherapy. <b>C</b>) 2-LTRs were detectable pre-chemotherapy in 2 of 9 patients versus detectable in 3 of 9 post-chemotherapy. Patients with undetectable 2-LTRs at both time points are not shown. Open symbols indicate undetectable samples.