<p>Immunofluorescence double staining of 53BP1 (green) and pATM (red) in blood lymphocytes of healthy individuals (ATM<sup>+/+</sup>) and ATM<sup>−/−</sup> homozygotes, analysed 24 h after irradiation with 2Gy compared to un-irradiated control. Deoxyribonucleic acid was counterstained with 4′,6-diamidino-2-phenylindole (blue), and images were merged to determine co-localization (yellow). Original magnification, x600.</p
Aim: to compare the amount of DNA single-strand breaks (SSB) and alkali-labile sites (ALS) induced b...
ABSTRACT Ionizing radiation induces DNA double strand breaks (DSBs) that trigger phosphorylation of ...
<p>(A) Grey scale immunofluorescent images of 53BP1, γ-H2AX and DAPI in irradiated lymphocytes and c...
<p>The tiny green dots represent one γ-H2AX focus (thin arrow) in human blood lymphocytes (thick arr...
DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated by the D...
<div><p>DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated ...
International audiencePURPOSE: By allowing the visualization of the proteins inside cells, the immun...
<p>(A) Time-line of Dna2-focus formation following 2 Gy γ-ray irradiation at time zero in <i>wild-ty...
<p>(A) Persistent DNA damage foci were visualized by immunofluorescence. Wt and <i>Ku80</i><sup>−/−<...
<p>(<b>A</b>) <i>Left panel</i>, Incidence of γ-H2AX foci in human and macaque blood samples irradia...
Lymphocytes are known to be sensitive to ionizing radiation, but the crucial factor causing this hyp...
DNA double-strand breaks (DSBs) are particularly lethal and genotoxic lesions, that can arise either...
DNA double-strand breaks (DSBs) represent an important radiation-induced lesion and impaired DSB rep...
<p>Typical examples of co-immunostaning of centromeres (red) and γ-H2AX (green). DNA was stained blu...
DNA double strand breaks (DSBs) pose a severe hazard to the genome as erroneous rejoining of DSBs ca...
Aim: to compare the amount of DNA single-strand breaks (SSB) and alkali-labile sites (ALS) induced b...
ABSTRACT Ionizing radiation induces DNA double strand breaks (DSBs) that trigger phosphorylation of ...
<p>(A) Grey scale immunofluorescent images of 53BP1, γ-H2AX and DAPI in irradiated lymphocytes and c...
<p>The tiny green dots represent one γ-H2AX focus (thin arrow) in human blood lymphocytes (thick arr...
DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated by the D...
<div><p>DNA double strand break (DSB) formation induced by ionizing radiation exposure is indicated ...
International audiencePURPOSE: By allowing the visualization of the proteins inside cells, the immun...
<p>(A) Time-line of Dna2-focus formation following 2 Gy γ-ray irradiation at time zero in <i>wild-ty...
<p>(A) Persistent DNA damage foci were visualized by immunofluorescence. Wt and <i>Ku80</i><sup>−/−<...
<p>(<b>A</b>) <i>Left panel</i>, Incidence of γ-H2AX foci in human and macaque blood samples irradia...
Lymphocytes are known to be sensitive to ionizing radiation, but the crucial factor causing this hyp...
DNA double-strand breaks (DSBs) are particularly lethal and genotoxic lesions, that can arise either...
DNA double-strand breaks (DSBs) represent an important radiation-induced lesion and impaired DSB rep...
<p>Typical examples of co-immunostaning of centromeres (red) and γ-H2AX (green). DNA was stained blu...
DNA double strand breaks (DSBs) pose a severe hazard to the genome as erroneous rejoining of DSBs ca...
Aim: to compare the amount of DNA single-strand breaks (SSB) and alkali-labile sites (ALS) induced b...
ABSTRACT Ionizing radiation induces DNA double strand breaks (DSBs) that trigger phosphorylation of ...
<p>(A) Grey scale immunofluorescent images of 53BP1, γ-H2AX and DAPI in irradiated lymphocytes and c...