<p>(A) Betulin derivative BT06; (B) Betulinic acid derivative AB13. Values are expressed as means and SEM. Cultures of log-phase promastigotes (2×10<sup>6</sup> cells.ml<sup>−1</sup>) were incubated at 26°C for 24 h at different compound concentrations.</p
Betulin, a naturally occurring abundant triterpene is converted in four steps to 3,28-di-O-acetyllup...
Background: Pentavalent antimonials are still the first choice treatment for leishmaniasis, but wit...
Leishmania infantum promastigotes and amastigotes were axenically cultured and exposed to the known ...
<p>Cultures of log-phase promastigotes (2×10<sup>6</sup> cells.ml<sup>−1</sup>) were incubated at 26...
The toxicity and antileishmanial activity of 20 betulin derivatives were studied. The toxicity of be...
Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting more than 1...
Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting more than 1...
<p>Flow cytometry analysis of <i>Leishmania infantum</i> promastigotes treated with betulin and betu...
<p>Promastigotes were incubated at 26°C for 24 h in the absence (A and C) or presence of betulin der...
Leishmaniasis is a public health problem in tropical and subtropical areas of the world, including V...
M. Unlike CPT, these compounds do not stabilize the cleavage complex, rather they abrogate the coval...
<p>Hanging dropin phase contrast (A, B, magnification 200×) and Giemsa staining (C, D, magnification...
Herein, we evaluated in vitro the anti-leishmanial activity of betulin derivatives in Venezuelan iso...
Betulin (lup-20(29)-ene-3ß,28-diol) is an abundant naturally occurring triterpene, and it is found p...
Cutaneous leishmaniasis (CL) due to L. braziliensis is associated with an exaggerated inflammatory r...
Betulin, a naturally occurring abundant triterpene is converted in four steps to 3,28-di-O-acetyllup...
Background: Pentavalent antimonials are still the first choice treatment for leishmaniasis, but wit...
Leishmania infantum promastigotes and amastigotes were axenically cultured and exposed to the known ...
<p>Cultures of log-phase promastigotes (2×10<sup>6</sup> cells.ml<sup>−1</sup>) were incubated at 26...
The toxicity and antileishmanial activity of 20 betulin derivatives were studied. The toxicity of be...
Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting more than 1...
Leishmaniasis is a neglected tropical disease (NTDs), endemic in 88 countries, affecting more than 1...
<p>Flow cytometry analysis of <i>Leishmania infantum</i> promastigotes treated with betulin and betu...
<p>Promastigotes were incubated at 26°C for 24 h in the absence (A and C) or presence of betulin der...
Leishmaniasis is a public health problem in tropical and subtropical areas of the world, including V...
M. Unlike CPT, these compounds do not stabilize the cleavage complex, rather they abrogate the coval...
<p>Hanging dropin phase contrast (A, B, magnification 200×) and Giemsa staining (C, D, magnification...
Herein, we evaluated in vitro the anti-leishmanial activity of betulin derivatives in Venezuelan iso...
Betulin (lup-20(29)-ene-3ß,28-diol) is an abundant naturally occurring triterpene, and it is found p...
Cutaneous leishmaniasis (CL) due to L. braziliensis is associated with an exaggerated inflammatory r...
Betulin, a naturally occurring abundant triterpene is converted in four steps to 3,28-di-O-acetyllup...
Background: Pentavalent antimonials are still the first choice treatment for leishmaniasis, but wit...
Leishmania infantum promastigotes and amastigotes were axenically cultured and exposed to the known ...