Comparative microarray analysis reveals involvement of the PERK/ATF4/DDIT3 ER stress pathways.
- Mark Richards (539415)
- Chee Wee Phoon (539416)
- Gwendoline Tze Wei Goh (539417)
- Eng Khuan Seng (539418)
- Xu Ming Guo (539419)
- Cherine Mei Fong Tan (539420)
- Woon-Khiong Chan (539421)
- Joel Mun Kin Lee (539422)
Publication date
March 2014
DOIAbstract
<p>Clustering of key differentially upregulated ER stress genes in BGO1V following 6 µM JC011 (<b>A</b>). Top 10 components of the PERK/ATF4/DDIT3 ER stress pathway that were found to be rapidly upregulated in JC011 treated BGO1V cells (<b>B</b>). qRT-PCR confirmation of upregulated UPR/ER stress pathway genes following JC011 treatment (<b>C</b>).</p
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