Average number of copy number aberrations (CNAs) and percentage of genome affected per MSS cohort.

<p>A) Average number of CNAs delineated by length per cancer in each MSS cohort. MSS cohorts had a similar number of overall CNAs occurring per cancer, however the <i>BRAF</i>mut/MSS cancers showed a greater number of focal CNAs, with the <i>BRAF</i>wt/MSS cancers having a greater number of whole arm events. <i>BRAF</i>mut/MSI cancers had considerably fewer CNAs of all types. B) Average percentage of genome affected by CNAs delineated by length in each MSS cohort. <i>BRAF</i>wt/MSS cancers had the greatest proportion of genome affected by CNA events, which was due to the higher number of whole arm events in this cohort. <i>BRAF</i>mut/MSS cancers showed a lower proportion of the genome affected by CNAs, which is reflective of the comparably lower rate of whole arm and higher rate of focal events that occurred compared to <i>BRAF</i>wt/MSS cancers.