<p>All are kinase inhibitors that were approved for clinical use at Nov. 2013.</p
The number of protein kinase inhibitors (PKIs) approved worldwide continues to grow steadily, with 3...
The deposition contains data sets of human and mouse protein kinase inhibitors with reliable activit...
The deposition contains 262 allosteric human protein kinase inhibitors for which X-ray structures of...
The aberrant activation of protein kinases is associated with many human diseases, most notably canc...
<p>PP2 (A) and compound 5 (B) are Src-family tyrosine kinases inhibitors, while CI-1040 (C) and PD 1...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
Drug discovery programs frequently target members of the human kinome and try to identify small mole...
Structural genomics (SG) has significantly increased the number of novel protein structures of targe...
Kinase inhibitor research is a comparatively recent branch of medicinal chemistry and pharmacology a...
SummarySmall-molecule kinase inhibitors have typically been designed to inhibit wild-type kinases ra...
Small-molecule kinase inhibitors have typically been designed to inhibit wild-type kinases rather th...
Protein kinases have emerged as one of the most important drug target families for the treatment of ...
The number of protein kinase inhibitors (PKIs) approved worldwide continues to grow steadily, with 3...
The deposition contains data sets of human and mouse protein kinase inhibitors with reliable activit...
The deposition contains 262 allosteric human protein kinase inhibitors for which X-ray structures of...
The aberrant activation of protein kinases is associated with many human diseases, most notably canc...
<p>PP2 (A) and compound 5 (B) are Src-family tyrosine kinases inhibitors, while CI-1040 (C) and PD 1...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
During the last two decades, kinase inhibitors have become the major drug class for targeted cancer ...
Drug discovery programs frequently target members of the human kinome and try to identify small mole...
Structural genomics (SG) has significantly increased the number of novel protein structures of targe...
Kinase inhibitor research is a comparatively recent branch of medicinal chemistry and pharmacology a...
SummarySmall-molecule kinase inhibitors have typically been designed to inhibit wild-type kinases ra...
Small-molecule kinase inhibitors have typically been designed to inhibit wild-type kinases rather th...
Protein kinases have emerged as one of the most important drug target families for the treatment of ...
The number of protein kinase inhibitors (PKIs) approved worldwide continues to grow steadily, with 3...
The deposition contains data sets of human and mouse protein kinase inhibitors with reliable activit...
The deposition contains 262 allosteric human protein kinase inhibitors for which X-ray structures of...
DOI
Add to ORKG