Effect of LDR on renal TNF-α levels in type 2 diabetic mice.

<p>Renal tissues from different groups were collected at the indicated times for measuring TNF-α expression at the mRNA (A) and protein (B) levels with RT-PCR and western blotting, respectively. (C) The location of TNF-α in the kidney was detected by immunohistochemical staining, at 400× magnification. Data are presented as means ± SEM. n = 9 in diabetic group and n = 8 in each other group. *<i>p</i><0.05 vs. the corresponding control group; #<i>p</i><0.05 vs. the corresponding DM group; $, <i>p</i><0.05 vs. DM group at the 4-week time-point.