<p>Indicated splenocytes were stimulated through the BCR and imaged after 30(A) Representative images. (B) Quantitative analysis of three independent experiments (p<0.001 for <i>Cblb<sup>−/−</sup></i> vs <i>Cblb<sup>C373A</sup></i> or WT).</p
<p>(A) BLECs were obtained by the co-culture of CD34<sup>+</sup>-derived ECs with pericytes for 6 da...
<p>(A) Quantification of Bcl-2 transcripts by RT-PCR. (B) Western blot analysis of endogenous Bcl-2 ...
B cells detect foreign antigens through their B cell antigen receptor (BCR). The BCR, when engaged b...
<p>(A–B) Trafficking to Lamp-1<sup>+</sup> and Cathepsin L<sup>+</sup> endocytic compartments by the...
<p>(A) Schematic representation of different Cbl-b mutants that were used to reconstitute Cblb<i><su...
<p>(A) Schematic representation of Cbl-b and c-Cbl encoding constructs used to reconstitute <i>Cblb<...
<p>WT splenic B cells were stimulated through the BCR for the indicated times. (A) Representative co...
Receptor endocytosis down-regulates ligand-induced signaling in a timely manner and depends on cytos...
<div><p>A20IIA1.6 cells expressing chimeras containing the cytosolic tail of either wild-type Igα or...
Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by tagging ...
<div><p>Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by ...
<div><p>Bulk unsorted splenocytes or magnetic bead–enriched CD19<sup>+</sup> splenocytes from infect...
CBL proteins are E3 ubiquitin ligases and adaptor proteins. The mammalian homologs – CBL, CBL-B and ...
<p>A) Left panel: evaluation of PTEN levels of expression in BCR-ABL-pcDNA3.1 transfected NIH3T3. Ri...
Abnormalities of molecules involved in signal transduction pathways are connected to Chronic Lymphoc...
<p>(A) BLECs were obtained by the co-culture of CD34<sup>+</sup>-derived ECs with pericytes for 6 da...
<p>(A) Quantification of Bcl-2 transcripts by RT-PCR. (B) Western blot analysis of endogenous Bcl-2 ...
B cells detect foreign antigens through their B cell antigen receptor (BCR). The BCR, when engaged b...
<p>(A–B) Trafficking to Lamp-1<sup>+</sup> and Cathepsin L<sup>+</sup> endocytic compartments by the...
<p>(A) Schematic representation of different Cbl-b mutants that were used to reconstitute Cblb<i><su...
<p>(A) Schematic representation of Cbl-b and c-Cbl encoding constructs used to reconstitute <i>Cblb<...
<p>WT splenic B cells were stimulated through the BCR for the indicated times. (A) Representative co...
Receptor endocytosis down-regulates ligand-induced signaling in a timely manner and depends on cytos...
<div><p>A20IIA1.6 cells expressing chimeras containing the cytosolic tail of either wild-type Igα or...
Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by tagging ...
<div><p>Casitas B-lineage lymphoma-b (Cbl-b) is a ubiquitin ligase (E3) that modulates signaling by ...
<div><p>Bulk unsorted splenocytes or magnetic bead–enriched CD19<sup>+</sup> splenocytes from infect...
CBL proteins are E3 ubiquitin ligases and adaptor proteins. The mammalian homologs – CBL, CBL-B and ...
<p>A) Left panel: evaluation of PTEN levels of expression in BCR-ABL-pcDNA3.1 transfected NIH3T3. Ri...
Abnormalities of molecules involved in signal transduction pathways are connected to Chronic Lymphoc...
<p>(A) BLECs were obtained by the co-culture of CD34<sup>+</sup>-derived ECs with pericytes for 6 da...
<p>(A) Quantification of Bcl-2 transcripts by RT-PCR. (B) Western blot analysis of endogenous Bcl-2 ...
B cells detect foreign antigens through their B cell antigen receptor (BCR). The BCR, when engaged b...