H3K4me3 level in H2A.Z- and H3.3-enriched regions.

<p>The genome was divided into 150 nucleotide bins, and the bins in which a particular variant was significantly enriched was determined as described in Materials and Methods (<i>see </i><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092689#pone.0092689.s004" target="_blank">Figure S4</a>). (A) Boxplot of H3K4me3 levels in H2A-and-H3-variant-enriched bins. (B) Boxplot of H3K4me3 levels in H2A.Z- or H3.3-, and both H2A.Z and H3.3 (H2A.Z/H3.3)-enriched bins. The bottom and top of the box are the 25th and 75th percentile, respectively, and the upper and lower whiskers represent 2.5th and 97.5th percentile, respectively. <i>P</i>-values were calculated using Mann–Whitney U-tests; (*) <i>P</i><0.001.