Labeling of lesions in DWI imaging according to the FLAIR pattern.

<p>A) In case of a FLAIR lesion encompassing the whole DWI-lesion, the hyperintensity was delineated as a region of interest (ROI) (A, second row). The FLAIR-ROI was then copied on the DWI and filled with 6 mm circular ROIs (A, third row)). These ROIs were classified as FLAIR+. B) In cases, in which the FLAIR-ROI did not completely match the DWI-lesion (B, second row), ROIs inside the FLAIR-ROI were classified as FLAIR+, and those outside as FLAIR- (B, third row). C) If no FLAIR lesion was identified (C, second row), the whole DWI lesion was filled with circular ROIs, which were classified as FLAIR- (C, third row). These steps were performed equally in ADC-maps. D), E) and F) show examples in analogy to the scheme, D) showing a patient, where the delineated FLAIR-ROI encompasses the whole DWI-lesion, E) depicting a patient, where the FLAIR-lesion only partially covers the DWI-lesion. Lastly, F) shows a patient, where all DWI-ROIs were labelled as FLAIR- in the absence of a visible FLAIR lesion.