<p>The red pins indicate DLT and the size of the pins correspond to the time to DLT since patients are given the treatment. The green pins indicate that a patient did not experience DLT within one cycle of treatment.</p
<p>Note: The numbers in parentheses represent the results in LNs and those not in parentheses repres...
Flow diagram of patients enrolled in the TrEAT TD clinical trial and paired samples that were includ...
Percentage of trials with the estimated MTD inside the toxicity optimal interval and average percent...
<p>MTD: dose maximal tolerated dose;</p><p>*: p<0.05.</p><p>The total of trials within the same trea...
<p>Example of one patient’s determination of LOED based on MTX doses over time along with estimated ...
<p>The separated boxes indicate different clusters/states. The width of the boxes indicates the time...
<p>Serum DFMO concentration versus time measurements for three patients receiving 750 mg/m<sup>2</su...
Percentage of trials with the estimated MTD inside the optimal MTD interval and average percentage o...
Number of drugs above MIC over time plot of first-line drugs at steady state, collected as the fifth...
<p>The plot displays the study, sample size, weighted mean differences (WMD), confidence interval, a...
<p>DLI doses, donor chimerism and the clinical course following DLI are depicted during time after a...
<p>Note: The numbers in parentheses represent the results in LNs and those not in parentheses repres...
<p>MGC803 cells transfected with LGR5 and mock-transfected cells were compared. The black line with ...
<p>Legend: <sup>§</sup>The values of mean±SD are listed;</p>*<p>Comparison with respective controls;...
The visual predictive checks were simulated for 1,000 patients and are shown for all 7 drugs and 9 l...
<p>Note: The numbers in parentheses represent the results in LNs and those not in parentheses repres...
Flow diagram of patients enrolled in the TrEAT TD clinical trial and paired samples that were includ...
Percentage of trials with the estimated MTD inside the toxicity optimal interval and average percent...
<p>MTD: dose maximal tolerated dose;</p><p>*: p<0.05.</p><p>The total of trials within the same trea...
<p>Example of one patient’s determination of LOED based on MTX doses over time along with estimated ...
<p>The separated boxes indicate different clusters/states. The width of the boxes indicates the time...
<p>Serum DFMO concentration versus time measurements for three patients receiving 750 mg/m<sup>2</su...
Percentage of trials with the estimated MTD inside the optimal MTD interval and average percentage o...
Number of drugs above MIC over time plot of first-line drugs at steady state, collected as the fifth...
<p>The plot displays the study, sample size, weighted mean differences (WMD), confidence interval, a...
<p>DLI doses, donor chimerism and the clinical course following DLI are depicted during time after a...
<p>Note: The numbers in parentheses represent the results in LNs and those not in parentheses repres...
<p>MGC803 cells transfected with LGR5 and mock-transfected cells were compared. The black line with ...
<p>Legend: <sup>§</sup>The values of mean±SD are listed;</p>*<p>Comparison with respective controls;...
The visual predictive checks were simulated for 1,000 patients and are shown for all 7 drugs and 9 l...
<p>Note: The numbers in parentheses represent the results in LNs and those not in parentheses repres...
Flow diagram of patients enrolled in the TrEAT TD clinical trial and paired samples that were includ...
Percentage of trials with the estimated MTD inside the toxicity optimal interval and average percent...