<p><i>I-SceI</i>-induced HR-mediated repair was significantly decreased in the DR-GFP U2OS cell line with reduced ATR expression (<b>A</b>). For (<b>A</b>) ***<i>P<0.001</i> and n = 3. (B) A representative image of ATR expression knockdown using siRNA in the DR-GFP U2OS cells (siCtr is scramble).</p
ATR (ataxia telangiectasia and Rad-3-related) is a pro-tein kinase required for survival after DNA d...
Fondazione Italiana per la Ricerca sul Cancro FIRC 18112 Sina Atashpaz.Fondazione Umberto Veronesi S...
<p><b>A</b>) Each of the three SPR-proficient strains in our collection were incubated with siRNA po...
DNA replication fork stalling or collapse that arises from endogenous damage poses a serious threat ...
<p>Schematic representation of the <i>p<sup>un</sup></i> mutation (tandem duplication of exons 6–18)...
ATR is a key regulator of cell-cycle checkpoints and homologous recombination (HR). Paradoxically, A...
Homologous recombination (HR) is required for faithful repair of double-strand DNA breaks. Defects i...
ATRX is a chromatin remodeler that, together with its chaperone DAXX, deposits the histone variant H...
354 pagesCells constantly incur DNA damage arising from endogenous and exogenous sources. Homologous...
<div><p>(A) HeLa cells were transfected with nonspecific (NS) siRNA or siRNA targeted to ATR, or ATM...
<p>(<b>A</b>) Immunostaining of RPA (red and upper panel) in <i>TopBP1<sup>ki/+</sup></i> cells 36 h...
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce ...
DNA damage is a universal inducer of cell cycle arrest at the G2 phase. Infection by the human immun...
<p>(A) Knockdown of the ATM and ATR expression in HPr-1 AR cells. Cells were transiently transfected...
<p>H157 cells were transfected with non-targeting (siNT) or 53BP1 siRNA and then treated with 2.5μM ...
ATR (ataxia telangiectasia and Rad-3-related) is a pro-tein kinase required for survival after DNA d...
Fondazione Italiana per la Ricerca sul Cancro FIRC 18112 Sina Atashpaz.Fondazione Umberto Veronesi S...
<p><b>A</b>) Each of the three SPR-proficient strains in our collection were incubated with siRNA po...
DNA replication fork stalling or collapse that arises from endogenous damage poses a serious threat ...
<p>Schematic representation of the <i>p<sup>un</sup></i> mutation (tandem duplication of exons 6–18)...
ATR is a key regulator of cell-cycle checkpoints and homologous recombination (HR). Paradoxically, A...
Homologous recombination (HR) is required for faithful repair of double-strand DNA breaks. Defects i...
ATRX is a chromatin remodeler that, together with its chaperone DAXX, deposits the histone variant H...
354 pagesCells constantly incur DNA damage arising from endogenous and exogenous sources. Homologous...
<div><p>(A) HeLa cells were transfected with nonspecific (NS) siRNA or siRNA targeted to ATR, or ATM...
<p>(<b>A</b>) Immunostaining of RPA (red and upper panel) in <i>TopBP1<sup>ki/+</sup></i> cells 36 h...
The checkpoint kinases ATM (ataxia telangiectasia mutated) and ATR (ATM and Rad3 related) transduce ...
DNA damage is a universal inducer of cell cycle arrest at the G2 phase. Infection by the human immun...
<p>(A) Knockdown of the ATM and ATR expression in HPr-1 AR cells. Cells were transiently transfected...
<p>H157 cells were transfected with non-targeting (siNT) or 53BP1 siRNA and then treated with 2.5μM ...
ATR (ataxia telangiectasia and Rad-3-related) is a pro-tein kinase required for survival after DNA d...
Fondazione Italiana per la Ricerca sul Cancro FIRC 18112 Sina Atashpaz.Fondazione Umberto Veronesi S...
<p><b>A</b>) Each of the three SPR-proficient strains in our collection were incubated with siRNA po...