Simulated phosphorylation curve for the sequestration model and the ternary model.

<p>(A and B) FAK phosphorylation ratio as a function of the total c-Src concentration for three different raft-volume ratios in the sequestration model (A) and the ternary model (B). The black line denotes the raft-volume ratio <b><i>Vr</i></b> = 0.1 (control), the dashed line denotes <b><i>Vr</i></b> = 0.05, and the pointed line denotes <b><i>Vr</i></b> = 0.01. (C and D) FAK phosphorylation ratio as a function of the total Cbp concentration for three different raft-volume ratios in the sequestration model (C) and the ternary model (D). (E and F) The fold change in FAK phosphorylation level with respect to the raft-volume ratio <b><i>Vr</i></b>. The values are normalized by <b><i>Vr</i></b> = 0.1.