Analysis of cell homing and metastases of GSDMB transfectants by luciferase imaging.

<p>(A) Representative bioluminescence images of mice intracardially injected with luciferase-expressing MCF7-C (panels a, b, c), MCF7-G1 (panels d, e, f), and MCF7-G2 cells (panels g, h, j). Images were obtained at 0, 3 and 11 weeks after cell injection. The color scale represents the photon flux (photons per second) emitted from tumor cells. (B) Metastatic burden quantified by luciferin photon flux at 11 weeks after tumor injection (ovaries, bone, lungs and brain are shown) (C) Quantification of the percentage of organs with metastases. N = 5 mice per group. All experiments were performed in duplicate using 5 mice per experiment.