Protection by Hid/Rpr-induced cell death is sensitive to <i>ban</i> gene dosage.

<p>Wing imaginal discs from larvae carrying one copy each of <i>ptc4-GAL4</i>, <i>UAS-hid, UAS-rpr</i> and <i>tub-GAL80^ts</i> were fixed and stained for DNA (A, C, E) and cleaved Caspase 3 (B, D, F) at 4 h after irradiation with 0 (-IR) or 4000R (+IR) of X-rays. Additional genotypes were as indicated. (G) shows the timeline followed. In otherwise wild type background (D), areas outside the <i>ptc</i> domain showed reduced caspase staining reflecting protection in response to <i>ptc4>Hid/Rpr</i> (arrows). In contrast, the corresponding areas in <i>ban</i>/+ discs showed caspase activity (F, arrows).