Chronic Rb1 treatment reduced peripheral inflammation in obese mice fed a HF diet for 16 weeks.

<p>Protein expression of the pro-inflammatory cytokines TNF-α, IL-6 and IL-1β, as well as the inflammatory signaling molecules p-IKK and p-IκBα in the epididymal fat tissue (A) and liver (B) in HF-induced obese mice with Rb1 chronic treatment (n = 8). *<i>p</i><0.05 vs. HF diet control group, +<i>p</i><0.10 and >0.05 vs. HF control group. Data are presented as mean ± SEM.