Reverse and concordant task-rest interactions.

<p>The figure depicts activated clusters (whole-brain FWE-corrected) for the reverse task-rest interaction in the amygdala (A) and the concordant task-rest interaction in DLPFC and IPL (B) – the latter showing a representative time course for task-negative regions. Peak coordinates for these clusters can be obtained from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0093098#pone-0093098-t001" target="_blank">Table 1</a>. In addition, it shows the graphs of the grand mean right amygdala (C), right DLPFC (D), and right IPL (E) time courses (computed over blocks and participants) for regulated (red) and unregulated aversive (blue) and unregulated neutral (green) stimulation-fixation. Stimulation onset is at TR1, stimulation offset is at TR 4. The activation in response to the stimulation (shaded in gray) should be expected to be delayed by about 3 TRs which corresponds to the typical lag of the canonical hemodynamic response.