Therapeutic effects of X-ray irradiation on EL4 tumors in C57BL/6 mice.

<p>(A) Growth curves of EL4 tumors in the non-treated group (open circles, n = 5) and irradiated group (closed triangles, n = 5). X-ray irradiation was performed on Day 10; bars, SD. (B) Survival curves for EL4-inoculated C57BL/6 mice, the non-treated group (dotted line), and the irradiated group (solid line). (C) Lymph node metastasis (arrows) in a representative mouse 20 days after tumor inoculation. (D) Growth curve of EL4 tumors (second inoculation). EL4 cells were re-inoculated into the left hind limbs of mice 24 days after the first challenge with EL4 cells (closed triangles, n = 5) or B16 cells (open circles, n = 5); bars, S.D.