CD8⁺ T cells accumulate in brains of NKC congenic mice during <i>P. berghei</i> ANKA infection.

<p>BALB.B6-CT-1, BALB.B6-CT-6, BALB.B6-CT-12 and BALB.B6-CT-13 mice were infected with <i>P. berghei</i> ANKA. Brains were collected on day 7 p.i after extensive perfusion of the euthanised animals. The BSL were isolated, stained anti-TCR and anti-CD8 antibodies and analysed by flow cytometry. The percentage (<i>A</i>) and absolute number (<i>B</i>) of CD8⁺ T cells were calculated. Representative dot plots are shown. Each bar represents the mean of 7–8 samples obtained over 2 separate infection experiments that gave similar results ± SEM, **** P<0.0001 between BALB.B6-CT-12 and BALB.B6-CT-1; ***P<0.0005 between BALB.B6-CT-12 and BALB.B6-CT-6; ** P<0.01 between BALB.B6-CT-12 and BALB.B6-CT-13; *P<0.05 between BALB.B6-CT-13 and BALB.B6-CT-1.