Roles of Wor1 and Efg1 in the regulation of white-gray-opaque transitions in <i>C. albicans</i>.

<p>NA, not available. The complete switching frequency data under different conditions are shown in Figure S10. (A) White-gray switching frequencies (%) on YPD medium. The <i>wor1/wor1</i> mutant cannot switch to the opaque phenotype under all conditions tested. (B) Gray-opaque switching frequencies (%) on YPD medium. The <i>efg1/efg1</i> mutant cannot switch to the white phenotype under all conditions tested. (C) Switching frequencies (%) on YPD medium. The <i>wor1/wor1 efg1/efg1</i> double mutant is locked in the gray phase under all conditions tested. (D) Switching frequencies (%) on YPD medium of the wild type control (adapted from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1001830#pbio-1001830-g002" target="_blank">Figure 2A</a>). (E) Regulatory model of the white-gray-opaque tristable phenotypic switching system.