Mizoribine suppresses aldosterone-induced renal inflammation.
- Toshiki Doi (546060)
- Shigehiro Doi (546061)
- Ayumu Nakashima (430474)
- Toshinori Ueno (546062)
- Yukio Yokoyama (546063)
- Nobuoki Kohno (224941)
- Takao Masaki (546064)
Publication date
April 2014
DOIAbstract
<p>Aldosterone (ALD) induced considerable T lymphocyte and macrophage infiltration in the rat kidneys, whereas the infiltration was suppressed by mizoribine (MZR). (A) Representative photomicrographs of renal T lymphocyte infiltration (CD3 staining) and macrophage infiltration (CD68 staining). (B) Graphs show the quantification of CD3-positive and CD68-positive cells. Values are presented as mean ± SEM. *<i>P</i><0.05.</p
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