Classification of human CSF proteins significantly differentially expressed between WNND patients (<i>i.e.</i>, A2 group) and control individuals (<i>i.e.</i>, C2 and C3 groups) identified by quantitative LC-MS/MS analysis.

<p>(A) The number of proteins significantly differentially expressed between WNND group and AH+IIH control group or between AH and IIH control sub-groups are represented in the Venn diagram. (B) Venn diagram representation of proteins significantly differentially expressed between WNND group and AH or IIH control sub-groups, among the proteins found deregulated exclusively in patients with WNND compared to AH+IIH group (n = 47). The two groups that were compared are indicated below each circle. The number and the percentage of proteins associated with each category are indicated in brackets. Classification of the significantly differentially regulated proteins according to their sub-cellular location (C) and their functional categorization (D) according to gene ontology (GO). The percentages of proteins associated with each category are indicated. WNND, West Nile neuroinvasive disease; AH, acute headache; IIH, idiopathic intracranial hypertension; CSF, cerebrospinal fluid.