PSD-95 decreases acid-evoked currents in hippocampal neurons, and is dependent upon <i>ASIC2</i>.

<p><i>A</i>, Representative acid-evoked currents from wildtype or <i>ASIC2−/−</i> cultured mouse hippocampal neurons transfected with either GFP alone (<i>GFP</i>), or GFP and PSD-95 (<i>PSD-95</i>). <i>B</i>, Mean current densities evoked by pH 5.0 in the indicated groups of hippocampal neurons (<i>n</i> ≥10; *<i>P</i><0.01 compared to both wildtype untransfected and GFP groups).