<p>The network in panel A shows the set of potential edges to start with. The arrows indicate the direction of interaction. Note that in panel A the arrows may represent activation or inhibition. To avoid cluttering, we have not plotted the arrows for self-regulations, but we do allow them in our model. The final network in panel B was obtained using the network inference procedure that we propose in this paper. In panel C the genes associated with each node are listed.</p
<p>A: For genes that are associated with human diseases and immune pathways, larger dots correspond ...
<p>Nodes in the network represent key signaling molecules. Directed edges represent predicted causal...
<p>Shown are six genes, each with a regulatory region of length 2 and a coding region (underlined). ...
<p>The edges are colored in red, blue, green, orange, and black based on the predictive value of the...
A. Schematic diagram for deriving causal relationships in the KEI genetic network. Associations betw...
<p>The genes are depicted as <i>nodes</i> of causal network. The hypotheses genes are distinctly col...
<p>(<b>A</b>) The inputs to our subnetwork inference approach are phenotypes measured in a loss-of-f...
<p>Solid arrows denote true-positives and dashed arrows denote false-positives. True-negatives and f...
<p>For clearly understanding this graph, we state the nodes and edges as follows: enzymes, stimuli, ...
<p>A maximum authorized number of 35 genes were used to generate a network. Direct interactions betw...
<p>The left panel shows a schematic diagram of the network topology, reproduced from Dunn <i>et al.<...
<p>(A) A gene network can be described as a graph or as a matrix in which positive entries (green sq...
<p>A. Right panels display simulation results and data for mutant genotype, left panels show simulat...
<p>Each circle represents a gene whose expression level is denoted by . Interactions between genes a...
<p>(<b>A</b>) Architecture of the functional networks reproducing the gene expression profiles obser...
<p>A: For genes that are associated with human diseases and immune pathways, larger dots correspond ...
<p>Nodes in the network represent key signaling molecules. Directed edges represent predicted causal...
<p>Shown are six genes, each with a regulatory region of length 2 and a coding region (underlined). ...
<p>The edges are colored in red, blue, green, orange, and black based on the predictive value of the...
A. Schematic diagram for deriving causal relationships in the KEI genetic network. Associations betw...
<p>The genes are depicted as <i>nodes</i> of causal network. The hypotheses genes are distinctly col...
<p>(<b>A</b>) The inputs to our subnetwork inference approach are phenotypes measured in a loss-of-f...
<p>Solid arrows denote true-positives and dashed arrows denote false-positives. True-negatives and f...
<p>For clearly understanding this graph, we state the nodes and edges as follows: enzymes, stimuli, ...
<p>A maximum authorized number of 35 genes were used to generate a network. Direct interactions betw...
<p>The left panel shows a schematic diagram of the network topology, reproduced from Dunn <i>et al.<...
<p>(A) A gene network can be described as a graph or as a matrix in which positive entries (green sq...
<p>A. Right panels display simulation results and data for mutant genotype, left panels show simulat...
<p>Each circle represents a gene whose expression level is denoted by . Interactions between genes a...
<p>(<b>A</b>) Architecture of the functional networks reproducing the gene expression profiles obser...
<p>A: For genes that are associated with human diseases and immune pathways, larger dots correspond ...
<p>Nodes in the network represent key signaling molecules. Directed edges represent predicted causal...
<p>Shown are six genes, each with a regulatory region of length 2 and a coding region (underlined). ...