Course of eGFR and CrCl during pre-dialysis care.

<p>The course of eGFR and CrCl are presented for the total population (A) and stratified by the type of endpoint reached (combined poor health outcome; dialysis/transplantation/death, or end of follow-up/other endpoint, B). The black and grey dots indicate the mean and the error bars indicate the standard error of the mean (SEM). The time in months before reaching an endpoint is presented on the x-axis (−12 means that the measurement was 7–12 months before the moment of reaching an endpoint, −18 means 13–18 months etc). On the left y-axis, the mean (SEM) eGFR (ml/min/1.73 m²) is presented, and on the right y-axis the mean (SEM) CrCl (ml/min/1.73 m²).