<p>Jia-Ming Chang, Paolo Di Tommaso, and Cedric Notredame. TCS: A new multiple sequence alignment reliability measure to estimate alignment accuracy and improve phylogenetic tree reconstruction, Mol Biol Evol first published online April 1, 2014, doi:10.1093/molbev/msu117<br><br></p> <p>Multiple sequence alignment (MSA) is a key modeling procedure when analyzing biological se- quences. Homology and evolutionary modeling are the most common applications of MSAs. Both are known to be sensitive to the underlying MSA accuracy. In this work we show how this problem can be partly overcome using the transitive consistency score (TCS), an extended version of the T-Coffee scoring scheme. Using this local evaluation function we show that one can iden...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Multiple sequence aligners typically work by progressively aligning the most closely related sequenc...
Background The alignment of biological sequences is of chief importance to most evolutionary and co...
International audienceMultiple sequence alignment (MSA) is a key modeling procedure when analyzing b...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
This article introduces the Transitive Consistency Score (TCS) web server; a service making it possi...
Multiple sequence alignment is a fundamental part in many bioinformatics applications such as phylog...
International audienceMotivation: Most evolutionary analyses are based on pre-estimated multiple seq...
Motivation: Most evolutionary analyses are based on pre-estimated multiple sequence alignment. Wong ...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Multiple sequence alignment (MSA) is the basis for a wide range of comparative sequence analyses fro...
Highly accurate estimation of phylogenetic trees for large datasets is difficult, in part because mu...
Abstract.—The process of inferring phylogenetic trees from molecular sequences almost always starts ...
Constructing and analyzing phylogenetic trees is central to biological disciplines such as evolution...
textPhylogenetics is the study of evolutionary relationships. Phylogenetic trees and alignments pla...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Multiple sequence aligners typically work by progressively aligning the most closely related sequenc...
Background The alignment of biological sequences is of chief importance to most evolutionary and co...
International audienceMultiple sequence alignment (MSA) is a key modeling procedure when analyzing b...
The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps...
This article introduces the Transitive Consistency Score (TCS) web server; a service making it possi...
Multiple sequence alignment is a fundamental part in many bioinformatics applications such as phylog...
International audienceMotivation: Most evolutionary analyses are based on pre-estimated multiple seq...
Motivation: Most evolutionary analyses are based on pre-estimated multiple sequence alignment. Wong ...
Phylogenetic reconstructions are essential in genomics data analyses and depend on accurate multiple...
Multiple sequence alignment (MSA) is the basis for a wide range of comparative sequence analyses fro...
Highly accurate estimation of phylogenetic trees for large datasets is difficult, in part because mu...
Abstract.—The process of inferring phylogenetic trees from molecular sequences almost always starts ...
Constructing and analyzing phylogenetic trees is central to biological disciplines such as evolution...
textPhylogenetics is the study of evolutionary relationships. Phylogenetic trees and alignments pla...
Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Be...
Multiple sequence aligners typically work by progressively aligning the most closely related sequenc...
Background The alignment of biological sequences is of chief importance to most evolutionary and co...