The increased inflammatory cells in lungs from Bmpr2^delx4+ transgenic mice are primarily in the monocyte lineage.

<p>(<b>A</b>) Number of CD11b cells as a proportion of CD45+ leukocytes in the lung is increased in Rosa26-Bmpr2^delx4+ mice (p<.01 by ANOVA). (<b>B</b>) All categories of CD68 positive circulating cells showed significant increases (* = p<.05), with the increase numerically dominated by interstitial macrophages. (<b>C & D</b>) Some subtypes of alveolar macrophages and dendritic cells also show statistically significant increases (* = p<.05).