Activity and cytotoxicity of HDAC inhibitors in the in vitro HIV latency model.

<p>Latently infected primary CD4 T cells prepared from three independent healthy donors were treated with the indicated compounds continuously for 48 hours. EC₅₀ and CC₅₀ values were determined from each dose-dependent response using a multi-parameter algorithm. Data are mean ± SD from three independent experiments performed in quadruplicate.