Sagittal sections through the <i>nax</i> mutant and wild type cerebella at P17 immunostained with CaBP and statistical graphs.

<p>The lobules are indicated by Roman numerals. <b>A</b>) The cerebellum in the wild type developed normally with a lobulated vermis. <b>B</b>) The cerebellum in the <i>nax</i> mutant is smaller and underdeveloped, however the principal lobules in the vermis are present. <b>C</b>) Average brain weights (in grams (g) mean ± SEM) in the nax mutant and wild type at P19 indicate a significant decrease in weight of the nax brain. <b>D</b>) The rostrocaudal length of the nax mutant and wild type cerebellum at P6, P12, and P17, shows that the nax cerebellum is much smaller than the wild type. <b>E</b>) The Pcl/ml thickness in the nax mutant is smaller than that of the wild-type at P6 and P12, however it becomes larger at P17. <b>F</b>) The linear density of Pcs per 1 mm significantly decreases from P6 to P17 in the nax mutant, however it is higher than the linear density of Pcs in wild-type at every age. Scale bars: 500 um.