<p>Castrated males and noncastrated male and female BALB/c mice were infected with <i>Mycobacterium tuberculosis</i> strain H37Rv and euthanized at different time-points. The lungs from three different animals at each time-point were used to determine the gene expression of the indicated cytokine. Asterisks represent statistical significance between the represented groups.</p
<p>Male mice were infected intratracheally with <i>M. tuberculosis</i> strain H37Rv and after two mo...
<p>NFATp<sup>−/−</sup> and WT mice were infected with MTb and total RNA was purified from the lungs ...
<p>Fold increases in gene expression (relative to mock-infected mice) of the cytokines (A) IL-17, (C...
<p>Total RNA was prepared from the lungs of naïve WT (black symbols) and TNF-α deficient mice (grey ...
The lungs from infected and treated mice were macerated and ex-vivo stimulated with M.tb complete so...
<p>Indicated cytokines were measured in the BAL using ELISA. Data are representative of three indepe...
<p>(A) Viable bacterial numbers in the lungs of wild-type (WT) and Mincle<sup>−/−</sup> mice (n≥4) w...
<p>Mice were infected by intratracheal route with <i>Mycobacterium tuberculosis</i> H37Rv. A) Surviv...
<p>C57BL/6 and GKO mice were infected as indicated in the legend to <a href="http://www.plosone.org/...
The cellular phenotypes and the expression of cytokines were studied in the lungs of mice, using imm...
<p>(<b>a</b>) Kinetic analysis of frequency (filled circles) and number (opened circles) of activate...
<p>Real time PCR was carried out to estimate the mRNA expression for TNF-α, IL-1β, IL-12 and IL-10, ...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>Pulmonary mycobacterial load (CFUs/lung) and cellular infiltrate (% pneumonic areas) were quantif...
<p>(A) Inflammatory scores of H&E-stained sections of lungs during Mtb infection. At 28, 56, and 112...
<p>Male mice were infected intratracheally with <i>M. tuberculosis</i> strain H37Rv and after two mo...
<p>NFATp<sup>−/−</sup> and WT mice were infected with MTb and total RNA was purified from the lungs ...
<p>Fold increases in gene expression (relative to mock-infected mice) of the cytokines (A) IL-17, (C...
<p>Total RNA was prepared from the lungs of naïve WT (black symbols) and TNF-α deficient mice (grey ...
The lungs from infected and treated mice were macerated and ex-vivo stimulated with M.tb complete so...
<p>Indicated cytokines were measured in the BAL using ELISA. Data are representative of three indepe...
<p>(A) Viable bacterial numbers in the lungs of wild-type (WT) and Mincle<sup>−/−</sup> mice (n≥4) w...
<p>Mice were infected by intratracheal route with <i>Mycobacterium tuberculosis</i> H37Rv. A) Surviv...
<p>C57BL/6 and GKO mice were infected as indicated in the legend to <a href="http://www.plosone.org/...
The cellular phenotypes and the expression of cytokines were studied in the lungs of mice, using imm...
<p>(<b>a</b>) Kinetic analysis of frequency (filled circles) and number (opened circles) of activate...
<p>Real time PCR was carried out to estimate the mRNA expression for TNF-α, IL-1β, IL-12 and IL-10, ...
<p>IL12p70 (A), IFN-γ (B), TNF-α (C), IL-10 (D) and IL-4 (E) were quantified in 100 mg of lung homog...
<p>Pulmonary mycobacterial load (CFUs/lung) and cellular infiltrate (% pneumonic areas) were quantif...
<p>(A) Inflammatory scores of H&E-stained sections of lungs during Mtb infection. At 28, 56, and 112...
<p>Male mice were infected intratracheally with <i>M. tuberculosis</i> strain H37Rv and after two mo...
<p>NFATp<sup>−/−</sup> and WT mice were infected with MTb and total RNA was purified from the lungs ...
<p>Fold increases in gene expression (relative to mock-infected mice) of the cytokines (A) IL-17, (C...