<p>Immunostaining for Jenv, SPC, and CC10 expression in lung tissue from A<sub>JE</sub>JJenv infected WT (A to C), Akt1<sup>−/−</sup> (D to F), Akt2<sup>−/−</sup> (G to I), and Akt3<sup>−/−</sup> (J to L) mice at 10× magnification. Representative images of advanced neoplastic lesions show robust Jenv expression within all cells of the lung tumor (A, D, G, J). Representative images show lung tumors staining uniformly positive for SPC (B, E, H, K) and negative for CC10 (C, F, I, L).</p
A-C Quantification of total number of hyperplasias (A), adenomas (B) and carcinomas (C) in pre-treat...
<p><b>A</b>) Immunohistochemical staining of <i>Kras<sup>LA2</sup></i> lung tumor for mouse MMP10. H...
<p>(<b>A–D</b>) <sup>1</sup>H/<sup>19</sup>F overlay and <sup>1</sup>H T<sub>2</sub> images of mock-...
<p>Representative macroscopic images of individual lung lobes harvested from A<sub>JE</sub>JJenv inf...
<p>Illustration of A<sub>JE</sub>JJenv, the AAV vector used to express JSRV Env in mouse lungs (A). ...
<p>WT, Akt1<sup>−/−</sup>, Akt2<sup>−/−</sup> and Akt3<sup>−/−</sup> mice infected with A<sub>JE</su...
<p>Representative western blot images of 80<sub>JE</sub>JJenv infected WT (panel 1), Akt1<sup>−/−</s...
BACKGROUND: The phosphatidylinositol 3-kinase-regulated protein kinase, Akt, plays an important role...
Background: The phosphatidylinositol 3-kinase–regulated protein kinase, Akt, plays an important role...
<p>AKT2,3 and AKT1,3 double knockdown cells as well as control cells were injected subcutaneously in...
<p>The JSRV Env protein leads to activation of signals through both the PI3K/Akt and MAPK pathways l...
Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate...
Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate...
<p>(<b>A</b>) Histological examination of the lungs of the 10-week-old K<i>-ras</i><sup>LA1</sup> mi...
<p><b>Copyright information:</b></p><p>Taken from "Adoptively transferred human lung tumor specific ...
A-C Quantification of total number of hyperplasias (A), adenomas (B) and carcinomas (C) in pre-treat...
<p><b>A</b>) Immunohistochemical staining of <i>Kras<sup>LA2</sup></i> lung tumor for mouse MMP10. H...
<p>(<b>A–D</b>) <sup>1</sup>H/<sup>19</sup>F overlay and <sup>1</sup>H T<sub>2</sub> images of mock-...
<p>Representative macroscopic images of individual lung lobes harvested from A<sub>JE</sub>JJenv inf...
<p>Illustration of A<sub>JE</sub>JJenv, the AAV vector used to express JSRV Env in mouse lungs (A). ...
<p>WT, Akt1<sup>−/−</sup>, Akt2<sup>−/−</sup> and Akt3<sup>−/−</sup> mice infected with A<sub>JE</su...
<p>Representative western blot images of 80<sub>JE</sub>JJenv infected WT (panel 1), Akt1<sup>−/−</s...
BACKGROUND: The phosphatidylinositol 3-kinase-regulated protein kinase, Akt, plays an important role...
Background: The phosphatidylinositol 3-kinase–regulated protein kinase, Akt, plays an important role...
<p>AKT2,3 and AKT1,3 double knockdown cells as well as control cells were injected subcutaneously in...
<p>The JSRV Env protein leads to activation of signals through both the PI3K/Akt and MAPK pathways l...
Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate...
Lung cancer is the most common cause of cancer-related death worldwide. A poor overall survival rate...
<p>(<b>A</b>) Histological examination of the lungs of the 10-week-old K<i>-ras</i><sup>LA1</sup> mi...
<p><b>Copyright information:</b></p><p>Taken from "Adoptively transferred human lung tumor specific ...
A-C Quantification of total number of hyperplasias (A), adenomas (B) and carcinomas (C) in pre-treat...
<p><b>A</b>) Immunohistochemical staining of <i>Kras<sup>LA2</sup></i> lung tumor for mouse MMP10. H...
<p>(<b>A–D</b>) <sup>1</sup>H/<sup>19</sup>F overlay and <sup>1</sup>H T<sub>2</sub> images of mock-...