CD8⁺ T cell response to HLA-B57-restricted wild type and A3G/F-mutated epitopes.

<p>Responses of PBMC from HLA-matched subjects to wild type and mutant epitopes are shown on the Y-axis, as IFN-γ SFC (Spot Forming Cells)/10⁶ PBMC. <b>A.</b> Comparison of IFN-γ induction between wild type and a mutant form of the B57-restriced Gag epitope TSTLQEQIGW. <b>B.</b> Comparison of IFN-γ induction between wild type and 2 mutant forms of the B57-restriced Gag epitope KAFSPEVIP. <b>C.</b> Comparison of IFN-γ induction between wild type and a mutant form of the B57-restriced Gag epitope AISPRTLNAW. <b>D.</b> Comparison of IFN-γ induction between wild type and 7 mutant forms of the B57 restricted Nef epitope GPGVRYPLTFGWCY.