Repressive effects of TET on PGE₂ levels in sera, brain tissues, and cultured astroglia.

<p>(A, B) PGE₂ levels in the sera and brain tissues, respectively, were significantly increased after LPS stimulation and markedly suppressed by TET. (C) MTT analysis of astroglia viability <i>in vitro</i> in the presence of different concentrations of TET. (D) PGE₂ levels in LPS-treated astroglia were suppressed by TET in a dose-dependent manner. Values are shown as M±SD. *, <i>P</i><0.05.