Row by column arrangement for pooling of DNA samples.

<p>576 DNA samples (S<i>_n</i>) were arranged in six 96 well plates. These samples were pooled in 4 matrices of 12 rows by 12 columns as illustrated. For each pool, 12 DNA samples were either pooled across the grid (row) or down the grid (column). Each pool of 12 DNA samples was then target enriched, barcoded and processed for Illumina sequencing.