PDGF-induced p21^WAF1/Cip1 (p21) expression.

<p><b>A</b>. PDGF-induced p21 mRNA expression in rat neonatal cardiac fibroblasts. n = 4. <b>B</b>. Effect of adenoviral UCH-L1 overexpression on PDGF-induced p21 mRNA expression in rat neonatal cardiac fibroblasts. Quiescent cells were treated with or without PDGF-BB (20 ng/ml) for 6 h. n = 4. ns, no statistical significance. <b>C</b>. Effect of adenoviral UCH-L1 overexpression on PDGF-induced p21 protein expression in rat neonatal cardiac fibroblasts. Quiescent cells infected with Ad-control or Ad-UCH-L1 were treated with or without PDGF-BB (20 ng/ml) for 24 h. n = 4, *p<0.05. The results are representatives of 4 separated experiments.