Expression and DNA methylation analysis of <i>DPP4</i>.

<p>(A) Different DPP4 expression in hippocampal of HP rats (n = 3) and HR rats (n = 3). (B) Gray Analysis data of DPP4 expression in hippocampal between HP rats and HR rats, data were normalized to the housekeeping gene Tublin, *P<0.05. (C) Sketch map about the location of CpG island 1 and CpG island 2 in DNA sequence of <i>DPP4,</i> black box show the rang of CpG island, elliptic point mean CG site. (D) HP rats (n = 3) show less methylated CG sites than HR rats (n = 3) in <i>DPP4</i> CpG island 1. (E) HP rats (n = 3) show less methylated CG sites than HR rats (n = 3) in DPP4 CpG island 2. The percentage methylation ratio were statistic from three independent experiments, *<i>P</i><0.05.