No significant change in optic nerve diameter, axonal elongation and glia activation in control and doubleCKO mice.

<p>Both control and doubleCKO mice were collected six months after tamoxifen treatment. No significant change in the optic nerve diameter (A and D), SMI32 immunolabeling (B and E) and GFAP immunolabeling (C and F) is seen between control and doubleCKO mice. Scale bar equals to 100 µm.