<p>Effects of static and dynamic Ptm on β-actin (act, ∼42 KDa) (<b>A</b> and <b>B</b>) and α-tubulin (tub, ∼50 KDa) (<b>C</b> and <b>D</b>) in intact bovine airways after 90 min of mechanical loading with (<b>B</b> and <b>D</b>) or without (<b>A</b> and <b>C</b>) constriction assessed by Western blots. T0: time 0 before stretch, St: static Ptm. D: dynamic Ptm oscillation. GAPDH (∼35 KDa) is loading control. Data are normalized such that the mean of the dynamic group is unity.</p
Abstract—Airway smoothmuscle cells exhibit stiffening during contractile activation. This stiffening...
The ability of airway smooth muscle to alter its stiffness and contractility in response to mechanic...
Airway smooth muscle (ASM) is cyclically stretched during breathing, even in the active state, yet t...
<p>Effects of Ptm on the cross-bridge forming contractile proteins α-smooth muscle actin (ASMA, ∼42 ...
<p>Western blots are shown for integrin-β1 (Int, ∼140 KDa) and its phosphorylated form (ph-Int) (A a...
<p>Effects of Ptm on the cross-bridge activating contractile proteins MLCK (∼210 KDa) (<b>A</b> and ...
Recent reports suggest that tidal stretches do not cause significant and sustainable dilation of con...
<p>Single and double-labeled immunohistochemistry showing the distribution of β-actin, ASMA, the pol...
<p>The subcellular structures of actin and microtubule are similar during static and dynamic loading...
<p>The cytoskeleton and connection to ECM by integrins determine and regulate airway diameter throug...
Superimposition of length fluctuations on contracted ASM have shown to reduce active force and stiff...
<p>Effects of static or dynamic mechanical loading conditions are shown during acetylcholine-induced...
The airway smooth muscle undergoes an elastic transition during a sustained contraction, characteriz...
In isolated airway smooth muscle (ASM) strips, an increase or decrease in ASM length away from its c...
Stress and strain are omnipresent in the lung due to constant lung volume fluctuation associated wit...
Abstract—Airway smoothmuscle cells exhibit stiffening during contractile activation. This stiffening...
The ability of airway smooth muscle to alter its stiffness and contractility in response to mechanic...
Airway smooth muscle (ASM) is cyclically stretched during breathing, even in the active state, yet t...
<p>Effects of Ptm on the cross-bridge forming contractile proteins α-smooth muscle actin (ASMA, ∼42 ...
<p>Western blots are shown for integrin-β1 (Int, ∼140 KDa) and its phosphorylated form (ph-Int) (A a...
<p>Effects of Ptm on the cross-bridge activating contractile proteins MLCK (∼210 KDa) (<b>A</b> and ...
Recent reports suggest that tidal stretches do not cause significant and sustainable dilation of con...
<p>Single and double-labeled immunohistochemistry showing the distribution of β-actin, ASMA, the pol...
<p>The subcellular structures of actin and microtubule are similar during static and dynamic loading...
<p>The cytoskeleton and connection to ECM by integrins determine and regulate airway diameter throug...
Superimposition of length fluctuations on contracted ASM have shown to reduce active force and stiff...
<p>Effects of static or dynamic mechanical loading conditions are shown during acetylcholine-induced...
The airway smooth muscle undergoes an elastic transition during a sustained contraction, characteriz...
In isolated airway smooth muscle (ASM) strips, an increase or decrease in ASM length away from its c...
Stress and strain are omnipresent in the lung due to constant lung volume fluctuation associated wit...
Abstract—Airway smoothmuscle cells exhibit stiffening during contractile activation. This stiffening...
The ability of airway smooth muscle to alter its stiffness and contractility in response to mechanic...
Airway smooth muscle (ASM) is cyclically stretched during breathing, even in the active state, yet t...