<p>Per subject and per peptide, the predictive accuracy of IFN-γ ELISpot assay responses (N = 15 per cohort) and TNF-α and IL-10 CBA assay responses (N = 5 per cohort) was determined according to subject HLA type, as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094974#s4" target="_blank">Methods</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0094974#s2" target="_blank">Results</a>. Stacked bars illustrate the proportions of true and false positive predictions and true and false negative predictions per cohort and per cytokine.</p
<p>A comparison of the measured (black) vs. predicted (dashed) population-based epitope maps in HVTN...
<p><i>H pylori</i> infection status includes <i>H pylori</i> positive cases versus positive controls...
H. pylori elicits specific humoral and cellular immuneresponses inthemucosal immune system. However,...
<p>Supernatants from ELISpot assay cultures were assayed for multiple cytokine concentrations by cyt...
<p>A) <b>Representative human IFN-γ ELISpot images. Representative images of IFN-γ ELISpot we</b>lls...
H. pylori persists in the human stomach over decades and promotes several adverse clinical sequelae ...
<p>The total number of Gag epitopes (of 8–14 amino acids in length) recognized <i>in silico</i> by a...
<p>For each MHC allele, the number of predicted epitopes within a given synthetic peptide is shown o...
<p><b>A</b>: Fraction of the true positives among the top 1% predictions (PP1%) for the naturally pr...
<p>(A-B) Comparison of (A) the total magnitudes (<i>y axis</i>) of <i>ex vivo</i> ELISPOT IFN-γ T-ce...
Computational T-cell epitope prediction tools have been previously devised to predict potential huma...
Background: Helicobacter pylori remains a global health hazard, and vaccination would be ideal for i...
<p>The total number of Nef epitopes (of 8–14 amino acids in length) recognized <i>in silico</i> by a...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
Background: Despite an apparently active host response, Helicobacter pylori infection can persist fo...
<p>A comparison of the measured (black) vs. predicted (dashed) population-based epitope maps in HVTN...
<p><i>H pylori</i> infection status includes <i>H pylori</i> positive cases versus positive controls...
H. pylori elicits specific humoral and cellular immuneresponses inthemucosal immune system. However,...
<p>Supernatants from ELISpot assay cultures were assayed for multiple cytokine concentrations by cyt...
<p>A) <b>Representative human IFN-γ ELISpot images. Representative images of IFN-γ ELISpot we</b>lls...
H. pylori persists in the human stomach over decades and promotes several adverse clinical sequelae ...
<p>The total number of Gag epitopes (of 8–14 amino acids in length) recognized <i>in silico</i> by a...
<p>For each MHC allele, the number of predicted epitopes within a given synthetic peptide is shown o...
<p><b>A</b>: Fraction of the true positives among the top 1% predictions (PP1%) for the naturally pr...
<p>(A-B) Comparison of (A) the total magnitudes (<i>y axis</i>) of <i>ex vivo</i> ELISPOT IFN-γ T-ce...
Computational T-cell epitope prediction tools have been previously devised to predict potential huma...
Background: Helicobacter pylori remains a global health hazard, and vaccination would be ideal for i...
<p>The total number of Nef epitopes (of 8–14 amino acids in length) recognized <i>in silico</i> by a...
<p>Dot plots showing individual cytokine responses in subjects from active VL (n = 8), cured VL (n =...
Background: Despite an apparently active host response, Helicobacter pylori infection can persist fo...
<p>A comparison of the measured (black) vs. predicted (dashed) population-based epitope maps in HVTN...
<p><i>H pylori</i> infection status includes <i>H pylori</i> positive cases versus positive controls...
H. pylori elicits specific humoral and cellular immuneresponses inthemucosal immune system. However,...