DENV-1 DIII-E106 Fab structural interface.

<p>The structural interface of DENV-1 DIII-E106 Fab (described by the surface area of antibody, Ab<i>^a</i> and antigen, Ag<i>^b</i> that is buried <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Krissinel1" target="_blank">[24]</a> as well as shape complementarity, Sc<i>^c</i> in the complex <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Lawrence1" target="_blank">[23]</a>) is compared to previously determined anti-DENV and anti-WNV Fab complexes. PDB codes E16 – WNV E DIII, 1ZTX <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Nybakken1" target="_blank">[20]</a>; 1A1D-2 – DENV2 E DIII, 2R29 <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Lok1" target="_blank">[21]</a>; E53 – WNV E, 3I50 <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Cherrier1" target="_blank">[43]</a>; E111 – DENV1 E DIII, 4FFY <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Austin1" target="_blank">[33]</a>; 2H12 – DENV1 DIII, 4AL8 <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Midgley1" target="_blank">[17]</a>; 2H12 – DENV3 DIII, 4ALA <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Midgley1" target="_blank">[17]</a>; 2H12 – DENV4 DIII, 4AM0 <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Midgley1" target="_blank">[17]</a>; 4E11 – DENV1 DIII, 3UZQ <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Cockburn1" target="_blank">[10]</a>; 4E11 – DENV2 DIII, 3UZV <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Cockburn1" target="_blank">[10]</a>; 4E11 – DENV3 DIII, 3UZE <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Cockburn1" target="_blank">[10]</a>; 4E11 – DENV4 DIII, 3UYP <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004072#ppat.1004072-Cockburn1" target="_blank">[10]</a>.