<p>Expression levels of <i>Kras</i>-4A (a) and <i>Kras</i>-4B (b) isoforms were measured by qPCR in normal lung of 11 A/J and 11 C57BL/6 mice. * <i>P</i> = 7.1×10<sup>−5</sup>, ANOVA. The line within each box represents the median of square root transformed values; upper and lower edges of each box are 75<sup>th</sup> and 25<sup>th</sup> percentiles, respectively; upper and lower bars indicate the highest and lowest values less than one interquartile range from the extremes of the box.</p
<p><b>A,</b> Expression in mice on embryonic day 12 (E12), 14 (E14), 16 (E16) and 18 (E18) and postn...
<p>Sections of lungs from <i>Braf<sup>CA/+</sup></i> mice infected with LEX-iCL lentiviruses express...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(a) Genetic linkage analysis of expression levels (square root transformed) of two <i>Kras</i> tr...
<p>(a) Expression QTL analysis of <i>Kras</i> transcripts showed that square-root-transformed levels...
<p>Allelic ratios were determined by pyrosequencing for rs30022167 and rs29968550, which map in a re...
Pulmonary adenoma susceptibility 1 (Pas1) is the major locus responsible for lung tumor susceptibili...
Kras is the most frequently mutated ras family member in lung carcinomas, whereas Hras mutations are...
<p>QPCR gene expression analysis in lung parenchyma from sham (n = 5) and PM10sum-treated mice (n = ...
Trabajo presentado en el Ciclo de conferencias CIC, celebrada en modalidad virtual el 13 de mayo de ...
To examine the roles of endogenous K-ras 4A and K-ras 4B splice variants in tumorigenesis, murine lu...
<p>Six to eight week old LSL-<i>Kras, Rb1</i><sup><i>+/+</i></sup> and LSL-<i>Kras, Rb1</i><sup>∆L/∆...
Background: Liquid biopsy represents an innovative tool in precision oncology to overcome current li...
In mammals, the KRAS locus encodes two protein isoforms, KRAS4A and KRAS4B, which differ only in the...
<p><b>(A)</b> RNA expression levels of the four KRAS isoforms in HCT116 (black) and HKE3 (grey). Whi...
<p><b>A,</b> Expression in mice on embryonic day 12 (E12), 14 (E14), 16 (E16) and 18 (E18) and postn...
<p>Sections of lungs from <i>Braf<sup>CA/+</sup></i> mice infected with LEX-iCL lentiviruses express...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(a) Genetic linkage analysis of expression levels (square root transformed) of two <i>Kras</i> tr...
<p>(a) Expression QTL analysis of <i>Kras</i> transcripts showed that square-root-transformed levels...
<p>Allelic ratios were determined by pyrosequencing for rs30022167 and rs29968550, which map in a re...
Pulmonary adenoma susceptibility 1 (Pas1) is the major locus responsible for lung tumor susceptibili...
Kras is the most frequently mutated ras family member in lung carcinomas, whereas Hras mutations are...
<p>QPCR gene expression analysis in lung parenchyma from sham (n = 5) and PM10sum-treated mice (n = ...
Trabajo presentado en el Ciclo de conferencias CIC, celebrada en modalidad virtual el 13 de mayo de ...
To examine the roles of endogenous K-ras 4A and K-ras 4B splice variants in tumorigenesis, murine lu...
<p>Six to eight week old LSL-<i>Kras, Rb1</i><sup><i>+/+</i></sup> and LSL-<i>Kras, Rb1</i><sup>∆L/∆...
Background: Liquid biopsy represents an innovative tool in precision oncology to overcome current li...
In mammals, the KRAS locus encodes two protein isoforms, KRAS4A and KRAS4B, which differ only in the...
<p><b>(A)</b> RNA expression levels of the four KRAS isoforms in HCT116 (black) and HKE3 (grey). Whi...
<p><b>A,</b> Expression in mice on embryonic day 12 (E12), 14 (E14), 16 (E16) and 18 (E18) and postn...
<p>Sections of lungs from <i>Braf<sup>CA/+</sup></i> mice infected with LEX-iCL lentiviruses express...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...